×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
GeneticVariation
CLINVAR
Validation of denaturing high performance liquid chromatography as a rapid detection method for the identification of human INK4A gene mutations.
11687599 2001
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
CausalMutation
CLINVAR
Undifferentiated carcinoma with osteoclastic giant cells (UCOCGC) of the pancreas associated with the familial atypical multiple mole melanoma syndrome (FAMMM).
18813118 2008
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
GeneticVariation
CLINVAR
Tumor suppressor p16INK4A: structural characterization of wild-type and mutant proteins by NMR and circular dichroism.
8755727 1996
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
GeneticVariation
CLINVAR
The prevalence of CDKN2A germ-line mutations and relative risk for cutaneous malignant melanoma: an international population-based study.
16896043 2006
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
CausalMutation
CLINVAR
The prevalence of CDKN2A germ-line mutations and relative risk for cutaneous malignant melanoma: an international population-based study.
16896043 2006
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
GeneticVariation
CLINVAR
The p16INK4a/CDKN2A tumor suppressor and its relatives.
9823374 1998
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
CausalMutation
CLINVAR
The p16INK4a/CDKN2A tumor suppressor and its relatives.
9823374 1998
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
GeneticVariation
CLINVAR
The p.G23S CDKN2A founder mutation in high-risk melanoma families from Central Italy.
17992122 2007
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
GeneticVariation
CLINVAR
The missing puzzle piece: splicing mutations.
24294354 2013
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
CausalMutation
CLINVAR
The melanoma-associated 24 base pair duplication in p16INK4a is functionally impaired.
15945100 2005
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
CausalMutation
CLINVAR
The M53I mutation in CDKN2A is a founder mutation that predominates in melanoma patients with Scottish ancestry.
17171691 2007
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
CausalMutation
CLINVAR
The CDKN2A/p16(INK) (4a) 5'UTR sequence and translational regulation: impact of novel variants predisposing to melanoma.
26581427 2016
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
CausalMutation
CLINVAR
The CDKN2A (p16) gene and human cancer.
9132280 1997
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
CausalMutation
CLINVAR
Temperature-sensitive mutants of p16CDKN2 associated with familial melanoma.
8668202 1996
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
GeneticVariation
CLINVAR
Temperature-sensitive mutants of p16CDKN2 associated with familial melanoma.
8668202 1996
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
CausalMutation
CLINVAR
Swedish CDKN2A mutation carriers do not present the atypical mole syndrome phenotype.
20526219 2010
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
CausalMutation
CLINVAR
Surveillance of second-degree relatives from melanoma families with a CDKN2A germline mutation.
23897584 2013
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
GeneticVariation
CLINVAR
Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a.
9751050 1998
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
GeneticVariation
CLINVAR
Role of the CDKN2A locus in patients with multiple primary melanomas.
15860862 2005
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
CausalMutation
CLINVAR
Role of key-regulator genes in melanoma susceptibility and pathogenesis among patients from South Italy.
19799798 2009
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
CausalMutation
CLINVAR
Risk of developing pancreatic cancer in families with familial atypical multiple mole melanoma associated with a specific 19 deletion of p16 (p16-Leiden).
10956390 2000
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
GeneticVariation
CLINVAR
Protective effect of copy number polymorphism of glutathione S-transferase T1 gene on melanoma risk in presence of CDKN2A mutations, MC1R variants and host-related phenotypes.
19484507 2009
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
CausalMutation
CLINVAR
Prospective risk of cancer and the influence of tobacco use in carriers of the p16-Leiden germline variant.
25227142 2015
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
GeneticVariation
CLINVAR
Prevalence of variations in melanoma susceptibility genes among Slovenian melanoma families.
18803811 2008
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Neoplastic Syndromes, Hereditary
0.110
CausalMutation
CLINVAR
Prevalence of p16 and CDK4 germline mutations in 48 melanoma-prone families in France. The French Familial Melanoma Study Group.
9425228 1998